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Irish Child Health Database - Peer Reviewed Papers

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Irish Child Health Database » » D » Dexamethasone/pharmacology

Dexamethasone/pharmacology

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1. Cardiac gene expression and synthesis of atrial natriuretic peptide in the nitrofen model of congenital diaphragmatic hernia in rats: effect of prenatal dexamethazone treatment

The aim of this study was to determine the gene and protein levels of atrial natriuretic peptide in the heart of nitrofen-induced congenital diaphragmatic hernia in rats and to evaluate the effect of antenatal dexamethazone treatment

Abstract:

BACKGROUND/PURPOSE:The aim of this study was to determine the gene and protein levels of atrial natriuretic peptide (ANP) in the heart of nitrofen-induced congenital diaphragmatic hernia (CDH) in rats and to evaluate the effect of antenatal dexamethazone (Dex) treatment. METHODS: CDH model was induced in pregnant rats after administration of 100 mg of nitrofen on day 9.5 of gestation more...

Categories:

antenatal dexamethazone treatment; congenital diaphragmatic hernia

Geography:

Republic of Ireland

J Pediatr Surg, Vol: 36 Page: 1497-501 October 2001
N. Guarino; H. Shima; P. Puri

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