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Irish Child Health Database - Peer Reviewed Papers

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Growth Substances/ metabolism

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1. Administration of antenatal glucocorticoids upregulates peptide growth factor gene expression in nitrofen-induced congenital diaphragmatic hernia in rats

The aim of this study was to investigate antenatal glucocorticoids administration effect on gene expression of basic fibroblast growth factor, platelet-derived growth factor transforming growth factor-beta1 in congenital diaphragmatic hernia

Abstract:

BACKGROUND/PURPOSE: There is increasing evidence to suggest that various growth factors play a crucial role in fetal lung growth and morphogenesis. An array of peptide growth factors regulate cell proliferation, differentiation, and various other cell functions in the developing lung. The aim of this study was to investigate the effect of antenatal glucocorticoids administration on gene more...

Categories:

antenatal glucocorticoids administration; congenital diaphragmatic hernia

Geography:

Republic of Ireland

J Pediatr Surg, Vol: 35 Page: 109-12 January 2000
T. Oue; H. Shima; Y. Taira; P. Puri

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