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The aim of this study was to investigate gene level expression of TR-alpha1 and TR-beta1 in the lung of nitrofen-induced congenital diaphragmatic hernia using reverse transcription polymerase chain reaction (RT-PCR)
Abstract:
PURPOSE: Thyroid receptor alpha-1 (TR-alpha1) and thyroid receptor beta-1 (TR-beta1) are thought to be essential for the fetal and postnatal development of the lung. The authors investigated gene level expression of TR-alpha1 and TR-beta1 in the lung of nitrofen-induced congenital diaphragmatic hernia (CDH) using reverse transcription polymerase chain reaction (RT-PCR). METHODS: CDH was more...
Categories:
TR-alpha1 and TR-beta1; congenital diaphragmatic hernia
Geography:
Republic of Ireland
J Pediatr Surg,
Vol: 36 Page: 1675-8 November 2001
H. Teramoto; N. Guarino; P. Puri
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The aim of this study was to evaluate the effect of antenatal glucocorticoid administration on ET-1 system in nitrofen-induced congenital diaphragmatic hernia hypoplastic lung in rats
Abstract:
BACKGROUND/PURPOSE: The hypoplastic lung and persistent pulmonary hypertension (PPH) are the principle causes of high mortality and morbidity in infants with congenital diaphragmatic hernia (CDH). Endothelin-1 (ET-1), which is produced by vascular endothelial cells and some leukocytes, plays a key role in modulating pulmonary vascular tone in PPH. Two different receptors (ET(A) and more...
Categories:
antenatal glucocorticoid; congenital diaphragmatic hernia lung
Geography:
Republic of Ireland
J Pediatr Surg,
Vol: 35 Page: 203-7 February 2000
H. Shima; T. Oue; Y. Taira; E. Miyazaki; P. Puri
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