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Irish Child Health Database - Peer Reviewed Papers

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Irish Child Health Database » » H » Hedgehog Proteins

Hedgehog Proteins

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  • 1.   Adriamycin induces notochord hypertrophy with conservation of sonic hedgehog expression in abnormal ectopic notochord in the adriamycin rat model

    The aim of this study was to test the hypothesis that Shh-expressing ectopic notochord could contribute to an increased volume of notochord relative to total embryo volume, resulting in an increased concentration of Shh in the notochord of embryos

    J Pediatr Surg, Vol: 39 Page: 859-63 June 2004
    A. Mortell; A. M. O'Donnell; S. Giles; J. Bannigan; P. Puri

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  • 2.   Notochord anomalies in the adriamycin rat model: A morphologic and molecular basis for the VACTERL association

    The aim of this study was to test the hypothesize that notochord anomalies allow ectopic expression of molecular signals in the developing embryo and thus lead to VACTERL malformations

    J Pediatr Surg, Vol: 38 Page: 469-73; discussion 469-73 March 2003
    J. Gillick; E. Mooney; S. Giles; J. Bannigan; P. Puri

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