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Irish Child Health Database - Peer Reviewed Papers

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Irish Child Health Database » » N » Nitric Oxide/physiology

Nitric Oxide/physiology

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1. Effect of nitric oxide on the development of nitrofen-induced fetal hypoplastic lung explants

The aim of this study was to evaluate the effect of nitric oxide on the morphogenesis of hypoplastic lung using nitrofen-induced rat lung explant model

Abstract:

BACKGROUND/PURPOSE: Nitric oxide (NO) is an important cell-signaling molecule, and its generators, nitric oxide synthases, are expressed temporospatially in fetal rat lung. Recently, NO has been reported to modulate branching of the fetal rat lung lobe in vitro. We designed this study to evaluate the effect of NO on the morphogenesis of hypoplastic lung using nitrofen-induced rat lung more...

Categories:

nitric oxide; hypoplastic lung

Geography:

Republic of Ireland

J Pediatr Surg, Vol: 40 Page: 17-21 January 2005
M. Shinkai; T. Shinkai; M. E. Pirker; S. Montedonico; P. Puri

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