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Irish Child Health Database - Peer Reviewed Papers

Database Search

How to use this database.

• Method 1- uses a free natural language approach.

  After choosing the object of the search – by ticking title, abstract, aims and objective, or author - enter a term, word or name in the ‘Search’ box to return references answering your research question.

• Method 2 - utilises key words.

  Those key words assigned from thesauruses of controlled vocabulary by the trained coders of international bibliographic databases.
  The controlled vocabularies key word are listed alphanumerically under 'Bibliographic database keywords' .
  Use the drop down menu to identity which 'key words' you are interested in to return references to answer your research question.

• Method 3 - is based on the indexing system

  developed by the researchers who compiled this database.
  It adopts a thematic approach to mapping Irish child health research. The themed areas represent outcomes mapped to the International Classification of Disease version 10 (ICD-10) or one of 23 other health-related themed outcomes. Themes are defined in Tables 5 to 7 (of the study report).
  Use the alphabetic drop down menu under ‘ICD-10 or themed health-related outcomes’ to identity which themed areas you are interested in to select references to answer your research question.

• Method 4 – allows papers to be searched by Study type.

  Indexing by study type offers a valuable insight into understanding the population impact of the topic of interest. More than 20 study types were identified across the 2,152 study papers. These are defined in Table 3 (of the study report). Within 'Study type' papers are further stratification by geographical region (Table 49), topic area of interest and study aims and objectives.
  Click on 'Study type' to select the type of study of interest, progressively select sub-categories by topic area or other sub-classification of interest to answer your research question.

The complete background, methods and findings from this mapping exercise are detailed in the study report.

Heme Oxygenase (Decyclizing)/ metabolism

Your search returns 3 documents

• 1.   Distribution of heme oxygenase-2 in nerves and interstitial cells of Cajal in the normal pylorus and in infantile hypertrophic pyloric stenosis

  The aim of this study was to examine the immunocolocalization of HO-2 and interstitial cells of Cajal in the normal pylorus and in infantile hypertrophic pyloric stenosis

  

  Abstract:

  CONTEXT: Interstitial cells of Cajal (ICCs) are pacemaker cells, which are of fundamental importance in regulating gastrointestinal motility. Recent evidence suggests that carbon monoxide is a neurotransmitter involved in neurotransmission between ICC and smooth muscle cells. Heme oxygenase-2 (HO-2) is the major physiological mechanism for the generation of carbon monoxide in the more...

  International Classification:

  Congenital malformations, deformations and chromosomal abnormalities - congenital hypertrophic pyloric stenosis

  Categories:

  hypertrophic pyloric stenosis; immunocolocalization of HO-2 and interstitial cells of Cajal; -infantile hypertrophic pyloric stenosis

  Geography:

  Republic of Ireland

  Arch Pathol Lab Med, Vol: 127 Page: 1182-6 September 2003
  A. P. Piotrowska; V. Solari; P. Puri

  [Preview] [Read]

• 2.   Expression of heme oxygenase-1 and endothelial nitric oxide synthase in the lung of newborns with congenital diaphragmatic hernia and persistent pulmonary hypertension

  The aim of this study was to examine the expression of HO-1 and endothelial nitric oxide synthase (eNOS) in the congenital diaphragmatic hernia lung

  

  Abstract:

  BACKGROUND/PURPOSE: Heme oxygenase (HO-1), an inducible isoform of HO is a regulator of vascular tone and cell proliferation through the production of endogenous carbon monoxide (CO). Endothelium-derived nitric oxide (NO) occurs in the endothelial layers of blood vessels and mediates vasorelaxation. Both CO and NO have similar properties and are potent vasodilators. The aim of this more...

  International Classification:

  Congenital malformations, deformations and chromosomal abnormalities - congenital diaphragmatic hernia

  Categories:

  endothelial nitric oxide synthase; -congenital diaphragmatic hernia lung

  Geography:

  Republic of Ireland

  J Pediatr Surg, Vol: 38 Page: 808-13 May 2003
  V. Solari; A. P. Piotrowska; P. Puri

  [Preview] [Read]

• 3.   Immunocolocalization of the heme oxygenase-2 and interstitial cells of Cajal in normal and aganglionic colon

  The aim of this study was to investigate the immunocolocalization of the HO-2 and interstitial cells of Cajal in normal and aganglionic bowel of Hirschsprung's disease

  

  Abstract:

  PURPOSE: Interstitial cells of Cajal (ICCs) are pacemaker cells that play an important role in the control of gut motility. Carbon monoxide (CO) has been proposed as an endogenous messenger molecule between ICC and smooth muscle cells in the gastrointestinal tract (GIT). Heme oxygenase-2 (HO-2) is the main physiologic mechanism for generating CO in human cells. The aim of this study was more...

  International Classification:

  Congenital malformations, deformations and chromosomal abnormalities - Other congenital malformations of the digestive system - Hirschsprung disease

  Categories:

  immunocolocalization of the HO-2 and interstitial cells of Cajal;-Hirschsprung's disease

  Geography:

  Republic of Ireland

  J Pediatr Surg, Vol: 38 Page: 73-7 January 2003
  A. P. Piotrowska; V. Solari; D. de Caluwe; P. Puri

  [Preview] [Read]