Irish Child Health Database - Peer Reviewed Papers
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The aim of this study was to test the hypothesize that the functional changes in the bladder following bladder outlet obstruction are due to alteration in cholinergic and sensory neuropeptide innervation
Abstract:
Posterior urethral valves (PUV) are the most common cause of bladder outlet obstruction (BOO) in infancy. Bladder instability, poor compliance and myogenic failure are responsible for the poor long-term prognosis in these patients. Previous studies have reported abundance of sensory neuropeptides, e.g. substance P (SP), calcitonin gene-related peptide (CGRP), vasoactive intestinal more...
Categories:
functional changes in the bladder; bladder outlet obstruction; neuropeptide innervation
Geography:
Republic of Ireland
Pediatr Surg Int,
Vol: 19 Page: 427-31 August 2003
B. Chertin; U. Rolle; S. Cascio; P. Puri
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The aim of this study was to describe the morphology and functional importance of the autonomic nervous system in the upper urinary tract
Abstract:
AIMS: The morphology and functional importance of the autonomic nervous system in the upper urinary tract is still not completely understood. Previous histological studies investigating the innervation of the urinary tract have mainly used conventional sections in which the three-dimensional structure of the intramural innervation is difficult to achieve. In contrast, the whole-mount more...
Categories:
the autonomic nervous system; upper urinary tract
Geography:
Republic of Ireland
Neurourol Urodyn,
Vol: 27 Page: 341-7 2008
U. Rolle; E. Brylla; B. Tillig; B. Chertin; S. Cascio; P. Puri
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The aim of this study was to investigate the role of nitric oxide in the pathogenesis of injury to the bladder mucosa after bladder outlet obstruction
Abstract:
OBJECTIVE: To investigate the role of nitric oxide (NO) in the pathogenesis of injury to the bladder mucosa after bladder outlet obstruction (BOO). MATERIALS AND METHODS: The response of bladder mucosa to BOO consists of thickening with fibrous connective tissue; NO is a multipurpose messenger important in blood vessel relaxation, neuronal communication and inflammatory activities of more...
Categories:
nitric oxide; bladder injury
Geography:
Republic of Ireland
BJU Int,
Vol: 94 Page: 392-9 August 2004
B. Chertin; U. Rolle; V. Solari; S. Cascio; P. Puri
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