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Irish Child Health Database - Peer Reviewed Papers

Database Search

How to use this database.

• Method 1- uses a free natural language approach.

  After choosing the object of the search – by ticking title, abstract, aims and objective, or author - enter a term, word or name in the ‘Search’ box to return references answering your research question.

• Method 2 - utilises key words.

  Those key words assigned from thesauruses of controlled vocabulary by the trained coders of international bibliographic databases.
  The controlled vocabularies key word are listed alphanumerically under 'Bibliographic database keywords' .
  Use the drop down menu to identity which 'key words' you are interested in to return references to answer your research question.

• Method 3 - is based on the indexing system

  developed by the researchers who compiled this database.
  It adopts a thematic approach to mapping Irish child health research. The themed areas represent outcomes mapped to the International Classification of Disease version 10 (ICD-10) or one of 23 other health-related themed outcomes. Themes are defined in Tables 5 to 7 (of the study report).
  Use the alphabetic drop down menu under ‘ICD-10 or themed health-related outcomes’ to identity which themed areas you are interested in to select references to answer your research question.

• Method 4 – allows papers to be searched by Study type.

  Indexing by study type offers a valuable insight into understanding the population impact of the topic of interest. More than 20 study types were identified across the 2,152 study papers. These are defined in Table 3 (of the study report). Within 'Study type' papers are further stratification by geographical region (Table 49), topic area of interest and study aims and objectives.
  Click on 'Study type' to select the type of study of interest, progressively select sub-categories by topic area or other sub-classification of interest to answer your research question.

The complete background, methods and findings from this mapping exercise are detailed in the study report.

Administration, Inhalation

Your search returns 9 documents

• 1.   A multicenter, randomized open study of early corticosteroid treatment (OSECT) in preterm infants with respiratory illness: comparison of early and late treatment and of dexamethasone and inhaled budesonide

  The aim of this study was to assess early corticosteroid treatment in preterm infants with respiratory illness compared early and late treatment and of dexamethasone and inhaled budesonide

  

  Abstract:

  AIM: To compare early (<3 days) with late (>15 days) steroid therapy and dexamethasone with inhaled budesonide in very preterm infants at risk of developing chronic lung disease. METHODS: Five hundred seventy infants from 47 neonatal intensive care units were enrolled. Criteria for enrollment included gestational age <30 weeks, postnatal age <72 hours, and need for mechanical more...

  International Classification:

  Evaluation of the effectiveness of treatments - preterm infants with respiratory illness

  Categories:

  preterm infants with respiratory illness

  Geography:

  International

  Pediatrics, Vol: 107 Page: 232-40 February 2001
  H. L. Halliday; C. C. Patterson; C. W. Halahakoon

  [Preview] [Read]

• 2.   Asthma management: in case of an exacerbation

  This article discusses the advantages of having a written asthma action plan to aid in recovery for an exacerbation of asthma

  

  Abstract:

  A written asthma action plan is the key to successful recovery from an exacerbation of asthma, whether managed at home or in hospital, writes Ursula Caulfield. more...

  Geography:

  Republic of Ireland

  World of Irish Nursing & Midwifery, Vol: 13 Page: 37-39 2005
  U. Caulfield

  [Preview] [Read]

• 3.   Ciclesonide versus other inhaled steroids for chronic asthma in children and adults

  The aim of this review was to assess the efficacy and adverse effects of ciclesonide relative to those of other inhaled corticosteroids in the management of chronic asthma

  

  Abstract:

  BACKGROUND: Inhaled corticosteroids (ICS) are an integral part of asthma management, and act as an anti-inflammatory agent in the airways of the lung. These agents confer both significant benefit in terms of symptom management and improvement in lung function, but may also cause harm in terms of local and systemic side-effects. Ciclesonide is a novel steroid that is metabolised to its more...

  International Classification:

  Systematic Review

  Categories:

  ciclesonide asthma

  Geography:

  Systematic Review

  Cochrane Database Syst Rev, 2008
  P. Manning; P. G. Gibson; T. J. Lasserson

  [Preview] [Read]

• 4.   Hypoglycemia due to adrenal suppression secondary to high-dose nebulized corticosteroid

  This case report discusses a 21-month-old asthmatic boy who had a hypoglycemic seizure during a proven acute adrenal crisis secondary to high-dose nebulized budesonide treatment.

  

  Abstract:

  High-dose inhaled corticosteroids, greater than 400 mcg per day of beclomethasone dipropionate or equivalent, can cause adrenal insufficiency, but a hypoglycemic crisis has not been reported with the use of nebulized corticosteroids. We describe a 21-month-old asthmatic boy who had a hypoglycemic seizure during a proven acute adrenal crisis secondary to high-dose nebulized budesonide more...

  International Classification:

  Diseases of the respiratory system - Report

  Categories:

  asthma; nebulized budesonide treatment

  Geography:

  Northern Ireland

  Pediatr Pulmonol, Vol: 34 Page: 85-6 July 2002
  K. A. Dunlop; D. J. Carson; M. D. Shields

  [Preview] [Read]

• 5.   Neonatal Ventilation With Inhaled Nitric Oxide Versus Ventilatory Support Without Inhaled Nitric Oxide for Preterm Infants With Severe Respiratory Failure: the INNOVO multicentre randomised controlled trial (ISRCTN 17821339)

  The aim of this study was to assess infants of <34 weeks' gestation, <28 days old, and with severe respiratory failure requiring ventilatory support to receive or not receive inhaled nitric oxide

  

  Abstract:

  BACKGROUND: Although inhaled nitric oxide (iNO) may be a promising treatment for newborn infants with severe respiratory failure, the results from 3 previous small trials were inconclusive. METHODS: Infants of <34 weeks' gestation, <28 days old, and with severe respiratory failure requiring ventilatory support were randomized to receive or not receive iNO. The study was not blinded. more...

  International Classification:

  Evaluation of the effectiveness of treatments - severe respiratory failure

  Categories:

  severe respiratory failure

  Geography:

  Republic of Ireland and the United Kingdom

  Pediatrics, Vol: 115 Page: 926-36 April 2005
  D. Field; D. Elbourne; A. Truesdale; R. Grieve; P. Hardy; A. C. Fenton; N. Subhedar; J. Ahluwalia; H. L. Halliday; J. Stocks; K. Tomlin; C. Normand

  [Preview] [Read]

• 6.   Neonatal ventilation with inhaled nitric oxide vs. ventilatory support without inhaled nitric oxide for infants with severe respiratory failure born at or near term: the INNOVO multicentre randomised controlled trial

  The aim of this study was to assess neonatal ventilation with inhaled nitric oxide vs. ventilatory support without inhaled nitric oxide for infants with severe respiratory failure born at or near term

  

  Abstract:

  BACKGROUND: Evidence from European centres to support the use of nitric oxide (NO) in mature newborns with evidence of severe respiratory failure is sparse. METHODS: Infants of >33 weeks' gestation, <28 days old, and with severe respiratory failure requiring ventilatory support were randomised to receive or not to receive inhaled NO (iNO). The study was not blinded. RESULTS: Sixty more...

  International Classification:

  Evaluation of the effectiveness of treatments - neonatal ventilation

  Categories:

  neonatal ventilation

  Geography:

  International

  Neonatology, Vol: 91 Page: 73-82 2007
  D. Field; D. Elbourne; P. Hardy; A. C. Fenton; J. Ahluwalia; H. L. Halliday; N. Subhedar; K. Heinonen; O. Aikio; R. Grieve; A. Truesdale; K. Tomlin; C. Normand; J. Stocks

  [Preview] [Read]

• 7.   Neurodevelopmental and respiratory follow-up results at 7 years for children from the United Kingdom and Ireland enrolled in a randomized trial of early and late postnatal corticosteroid treatment, systemic and inhaled (the Open Study of Early Corticosteroid Treatment)

  The aim of the study was to compare early school-age neurodevelopmental and respiratory outcomes for children treated with either early (<3/7) or delayed selective (>15/7) postnatal corticosteroid therapy comparing dexamethasone with budesonide treatment

  

  Abstract:

  OBJECTIVES: The goals were to compare early school-age neurodevelopmental and respiratory outcomes for children who were treated with either early (<3 days) or delayed selective (>15 days) postnatal corticosteroid therapy and to compare systemic dexamethasone treatment with inhaled budesonide treatment. METHODS: One hundred twenty-seven (84%) of 152 survivors from the United Kingdom and more...

  International Classification:

  Growth and development

  Categories:

  neurodevelopmental and respiratory outcomes

  Geography:

  Republic of Ireland and the United Kingdom

  Pediatrics, Vol: 117 Page: 2196-205 June 2006
  T. T. Wilson; L. Waters; C. C. Patterson; C. G. McCusker; N. M. Rooney; N. Marlow; H. L. Halliday

  [Preview] [Read]

• 8.   Prescribing patterns for asthma by general practitioners in six European countries

  This study aimed to examine current prescribing patterns for asthma by general practitioners in six European countries

  

  Abstract:

  To assess the level of concordance with international consensus on asthma management, we compared primary care prescribing patterns for asthma in different European countries. A prospective study of prescription items with an associated diagnostic label of asthma in patient consultations with a total of 235 general practitioners (GPs) from Belgium, England, Ireland, Italy, Northern more...

  International Classification:

  Practice/knowledge - asthma prescribing pattern

  Categories:

  asthma prescribing pattern

  Geography:

  International

  Respir Med, Vol: 94 Page: 578-83 June 2000
  G. Jepson; T. Butler; D. Gregory; K. Jones

  [Preview] [Read]

• 9.   Treatment of childhood asthma: how do the available options compare?

  This article discusses the available options for the treatment of childhood asthma

  

  Abstract:

  The National Asthma Council of Australia suggests that "the aim of preventive therapy should be to enable patients to enjoy a normal life (comparable with that of non-asthmatic children), with the least amount of medication and at minimal risk of adverse events. The level of maintenance therapy should be determined by symptom control and lung function in the interval periods." more...

  Geography:

  Republic of Ireland

  Paediatr Drugs, Vol: 5 Page: 685-98 2003
  D. Coghlan; C. Powell

  [Preview] [Read]