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Irish Child Health Database - Peer Reviewed Papers

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Irish Child Health Database » » C » Case-Control Studies

Case-Control Studies

Your search returns 61 documents

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  • 1.   A case control study of a deprivation triangle: teenage motherhood, poor educational achievement and unemployment

    The aim of this study was to compare the educational and employment experiences of teenage mothers and match peers from a similar social background

    Int J Adolesc Med Health, Vol: 14 Page: 117-23 2002 Apr-Jun
    T. Bradley; M. E. Cupples; H. Irvine

    [Preview] [Read]

  • 2.   A genome-wide DNA microsatellite association screen to identify chromosomal regions harboring candidate genes in diabetic nephropathy

    The aim of this study was to accelerate the identification of susceptibility genes in diabetic nephropathy using genome-wide fluorescence-based DNA microsatellite

    J Am Soc Nephrol, Vol: 17 Page: 831-6 March 2006
    A. J. McKnight; A. P. Maxwell; S. Sawcer; A. Compston; E. Setakis; C. C. Patterson; H. R. Brady; D. A. Savage

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  • 3.   A multivariate "time based" analysis of SIDS risk factors

    The aim of this study was to investigate the influence of analytical design on the variability of published results in studies on sudden infant death syndrome

    Arch Dis Child, Vol: 89 Page: 267-71 March 2004
    T. Matthews; M. McDonnell; C. McGarvey; G. Loftus; M. O'Regan

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  • 4.   A new predictor of cephalopelvic disproportion?

    The aim of this study was to examine new anthropomorphic parameters as indicators of Cephalopelvic disproportion

    J Obstet Gynaecol, Vol: 23 Page: 27-9 January 2003
    G. Connolly; C. Naidoo; R. M. Conroy; P. Byrne; P. McKenna

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  • 5.   Alterations in smooth muscle contractile and cytoskeleton proteins and interstitial cells of Cajal in megacystis microcolon intestinal hypoperistalsis syndrome

    The aim of study was to examine the expression of contractile and cytoskeleton proteins in smooth muscle contractile and distribution of interstitial cells of Cajal in megacystis microcolon intestinal hypoperistalsis syndrome bowel.

    J Pediatr Surg, Vol: 38 Page: 749-55 May 2003
    A. P. Piotrowska; U. Rolle; B. Chertin; D. De Caluwe; A. Bianchi; P. Puri

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  • 6.   Altered gene expression in highly purified enterocytes from patients with active coeliac disease

    The aim of this study was to examine gene expression in a highly purified isolate of enterocytes taken from patients with active coeliac disease

    BMC Genomics, Vol: 9 Page: 377 2008
    S. Bracken; G. Byrne; J. Kelly; J. Jackson; C. Feighery

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  • 7.   An 8 year study of risk factors for SIDS: bed-sharing versus non-bed-sharing

    The aim of this study was to measure the effect of bed-sharing during the last sleep period on risk factors for sudden infant death syndrome

    Arch Dis Child, Vol: 91 Page: 318-23 April 2006
    C. McGarvey; M. McDonnell; K. Hamilton; M. O'Regan; T. Matthews

    [Preview] [Read]

  • 8.   Analysis of the individual and aggregate genetic contributions of previously identified serine peptidase inhibitor Kazal type 5 (SPINK5), kallikrein-related peptidase 7 (KLK7), and filaggrin (FLG) polymorphisms to eczema risk

    The aim of this study was to analysis the individual and aggregate genetic contributions of previously identified serine peptidase inhibitor Kazal type 5 (SPINK5), kallikrein-related peptidase 7 (KLK7), and filaggrin (FLG) polymorphisms to eczema risk

    J Allergy Clin Immunol, Vol: 122 Page: 560-8 e4 September 2008
    S. Weidinger; H. Baurecht; S. Wagenpfeil; J. Henderson; N. Novak; A. Sandilands; H. Chen; E. Rodriguez; G. M. O'Regan; R. Watson; H. Liao; Y. Zhao; J. N. Barker; M. Allen; N. Reynolds; S. Meggitt; K. Northstone; G. D. Smith; C. Strobl; C. Stahl; T. Kneib; N. Klopp; T. Bieber; H. Behrendt; C. N. Palmer; H. E. Wichmann; J. Ring; T. Illig; W. H. McLean; A. D. Irvine

    [Preview] [Read]

  • 9.   Analysis of the MTHFR 1298A-->C and 677C-->T polymorphisms as risk factors for neural tube defects

    The aim of this study was to examine the association between the 1298A-->C polymorphism and 677C-->T polymorphism and neural tube defect in 276 complete triades (mother, father and child affected with an NTD)

    J Hum Genet, Vol: 48 Page: 190-3 2003
    A. Parle-McDermott; J. L. Mills; P. N. Kirke; V. B. O'Leary; D. A. Swanson; F. Pangilinan; M. Conley; A. M. Molloy; C. Cox; J. M. Scott; L. C. Brody

    [Preview] [Read]

  • 10.   Association between PRODH and schizophrenia is not confirmed

    The aim of this study was to examine the association between proline oxidase and schizophrenia

    Mol Psychiatry, Vol: 8 Page: 644-5 July 2003
    H. J. Williams; N. Williams; G. Spurlock; N. Norton; D. Ivanov; R. G. McCreadie; A. Preece; V. Sharkey; S. Jones; S. Zammit; I. Nikolov; I. Kehaiov; A. Thapar; K. C. Murphy; G. Kirov; M. J. Owen; M. C. O'Donovan

    [Preview] [Read]

  • 11.   Association of the interleukin 1 receptor antagonist gene with ulcerative colitis in Northern European Caucasians

    The aim of this study was to examine the association between the allele 2 of the interleukin 1 receptor antagonist gene

    Gut, Vol: 48 Page: 461-7 April 2001
    M. J. Carter; F. S. di Giovine; S. Jones; J. Mee; N. J. Camp; A. J. Lobo; G. W. Duff

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  • 12.   Association of transforming growth factor-beta1 gene polymorphism with reflux nephropathy

    The aim of this study was to investigate genotype frequencies for polymorphisms of the TGF-beta1 gene at position -509, codon 10 and 25, and examine circulating levels of TGF-beta1 in patients with reflux nephropathy

    J Urol, Vol: 174 Page: 1609-11; discussion 1611 October 2005
    V. Solari; D. Owen; P. Puri

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  • 13.   Atopy, home environment and the risk of childhood-onset type 1 diabetes: a population-based case-control study

    The aim of this study was to investigate atopy and home environment (such as children living at home, sharing a bedroom and house moves) as potential risk factors for type 1 diabetes

    Pediatr Diabetes, Vol: 9 Page: 191-6 June 2008
    C. R. Cardwell; D. J. Carson; J. Yarnell; M. D. Shields; C. C. Patterson

    [Preview] [Read]

  • 14.   Attachment styles and psychological profiles of child sex offenders in Ireland

    The aim of the study was to examine attachment styles and psychological profiles of child sex offenders in Ireland

    J Interpers Violence, Vol: 19 Page: 228-51 February 2004
    F. Marsa; G. O'Reilly; A. Carr; P. Murphy; M. O'Sullivan; A. Cotter; D. Hevey

    [Preview] [Read]

  • 15.   Automatic detection of gait events using kinematic data

    The aim of this study was to examine an algorithm which automatically determines the transitions between stance and swing phase of gait using kinematic data recorded by a motion capture system, which is routinely used in gait analysis laboratories.

    Gait Posture, Vol: 25 Page: 469-74 March 2007
    C. M. O'Connor; S. K. Thorpe; M. J. O'Malley; C. L. Vaughan

    [Preview] [Read]

  • 16.   Bacterial colonization of the prepuce in boys with vesicoureteral reflux who receive antibiotic prophylaxis

    The aim of the study was to examine the bacterial colonization of the prepuce in boys with vesicoureteral reflux who receive antibiotic prophylaxis

    J Pediatr, Vol: 139 Page: 160-2 July 2001
    S. Cascio; E. Colhoun; P. Puri

    [Preview] [Read]

  • 17.   Barriers to prenatal care in Europe

    The aim of this study was to examined the barriers to prenatal care uptake among pregnant women

    Am J Prev Med, Vol: 21 Page: 52-9 July 2001
    T. Delvaux; P. Buekens; I. Godin; M. Boutsen

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  • 18.   Children with stable asthma have reduced airway matrix metalloproteinase-9 and matrix metalloproteinase-9/tissue inhibitor of metalloproteinase-1 ratio

    The aim of this study was to examine the balance of MMP-8, MMP-9 and tissue inhibitor of metalloproteinases (TIMP)-1 in the airways of children with asthma

    Clin Exp Allergy, Vol: 35 Page: 1168-74 September 2005
    G. M. Doherty; S. V. Kamath; F. de Courcey; S. N. Christie; A. Chisakuta; J. D. Lyons; L. G. Heaney; M. Ennis; M. D. Shields

    [Preview] [Read]

  • 19.   Concentrations of antimony in infants dying from SIDS and infants dying from other causes

    The aim of this study was to determine concentrations of antimony in infants dying from sudden infant death syndrome and infants dying from other causes

    Arch Dis Child, Vol: 82 Page: 244-7 March 2000
    A. Cullen; B. Kiberd; D. Devaney; J. Gillan; P. Kelehan; T. G. Matthews; P. Mayne; N. Murphy; M. O'Regan; W. Shannon; L. Thornton

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  • 20.   Congenital anomalies and proximity to landfill sites

    The aim of this study was to quantify the occurrence of congenital anomalies in proximity to municipal landfill sites, was examined by small area, distance and clustering tendencies in relation to 83 landfills, five of which were major sites

    Ir Med J, Vol: 97 Page: 16-8 January 2004
    E. Boyle; H. Johnson; A. Kelly; R. McDonnell

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  • 21.   Construction of a high resolution linkage disequilibrium map to evaluate common genetic variation in TP53 and neural tube defect risk in an Irish population

    The aim of this study was to examine a high resolution linkage disequilibrium map to evaluate common genetic variation in TP53 and neural tube defect risk in an Irish population

    Am J Med Genet A, Vol: 146A Page: 2617-25 October 2008
    F. Pangilinan; K. Geiler; J. Dolle; J. Troendle; D. A. Swanson; A. M. Molloy; M. Sutton; M. Conley; P. N. Kirke; J. M. Scott; J. L. Mills; L. C. Brody

    [Preview] [Read]

  • 22.   Day-care and meningococcal disease in young children

    The aim of this study was to determine if day-care attendance was a risk factor for meningococcal disease

    Epidemiol Infect, Vol: 127 Page: 435-41 December 2001
    T. Grein; D. O'Flanagan

    [Preview] [Read]

  • 23.   Dental experience of cleft affected children in the west of Ireland

    The aim of this study was to examine caries experience and initial access to dental services in a group of children with cleft lip/palate in the west of Ireland

    Int Dent J, Vol: 51 Page: 73-6 April 2001
    A. R. Hewson; C. M. McNamara; T. F. Foley; J. R. Sandy

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  • 24.   Does maternal smoking increase the risk of neonatal polycythaemia?

    The aim of this study was to examine the relationship between tobacco smoking during pregnancy and neonatal Polycythaemia, and to assess the dose-response relationship

    Ir Med J, Vol: 93 Page: 175-6 September 2000
    E. al-Alawi; D. Jenkins

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  • 25.   Effect of second vaginal delivery on anal function in patients at risk of occult anal sphincter injury after first forceps delivery

    The aim of this study was to determine the effect of further vaginal delivery on anal sphincter function in women after apparently uncomplicated primiparous forceps delivery

    Dis Colon Rectum, Vol: 51 Page: 1361-6 September 2008
    R. Mahony; M. Behan; P. R. O'Connell; C. O'Herlihy

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  • 26.   Effect of social class at birth on risk and presentation of schizophrenia: case-control study

    The aim of this study was to examine whether low parental social class increases children's risk of subsequently developing Schizophrenia or modifies the presentation

    Bmj, Vol: 323 Page: 1398-401 December 2001
    F. Mulvany; E. O'Callaghan; N. Takei; M. Byrne; P. Fearon; C. Larkin

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  • 27.   Epidermal growth factor and monocyte chemotactic peptide-1 expression in reflux nephropathy

    The aim of this study was to define the expression of epidermal growth factor and monocyte chemotactic peptide-1 in severe reflux nephropathy in order to further understand the pathogenesis of reflux nephropathy

    Eur Urol, Vol: 44 Page: 144-9 July 2003
    B. Chertin; A. Farkas; P. Puri

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  • 28.   Evaluation of transcobalamin II polymorphisms as neural tube defect risk factors in an Irish population

    The aim of this study was to investigate whether six common polymorphisms in the TCII gene influence neural tube defect risk

    Birth Defects Res A Clin Mol Teratol, Vol: 73 Page: 239-44 April 2005
    D. A. Swanson; F. Pangilinan; J. L. Mills; P. N. Kirke; M. Conley; A. Weiler; T. Frey; A. Parle-McDermott; V. B. O'Leary; R. R. Seltzer; K. A. Moynihan; A. M. Molloy; H. Burke; J. M. Scott; L. C. Brody

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  • 29.   Evidence of an inflammatory pathologic condition in "normal" appendices following emergency appendectomy

    The aim of the study was to study appendix specimens for the expression of inflammatory markers as an indicator of presence of an inflammatory response in this subgroup of patients

    Arch Pathol Lab Med, Vol: 125 Page: 759-64 June 2001
    L. Nemeth; D. J. Reen; D. S. O'Briain; M. McDermott; P. Puri

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  • 30.   Expression of heme oxygenase-1 and endothelial nitric oxide synthase in the lung of newborns with congenital diaphragmatic hernia and persistent pulmonary hypertension

    The aim of this study was to examine the expression of HO-1 and endothelial nitric oxide synthase (eNOS) in the congenital diaphragmatic hernia lung

    J Pediatr Surg, Vol: 38 Page: 808-13 May 2003
    V. Solari; A. P. Piotrowska; P. Puri

    [Preview] [Read]

  • 31.   Factors relating to the infant's last sleep environment in sudden infant death syndrome in the Republic of Ireland

    The aim of this study was to identify risk factors for sudden infant death syndrome in the sleeping environment of Irish infants

    Arch Dis Child, Vol: 88 Page: 1058-64 December 2003
    C. McGarvey; M. McDonnell; A. Chong; M. O'Regan; T. Matthews

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  • 32.   Focally enhanced gastritis in children with Crohn's disease and ulcerative colitis

    This study aimed to evaluate the occurrence of focally enhance & other gastric histological abnormalities in children with inflammatory bowel disease and examine the utility of focally enhanced gastritis in determining ulcerative colitis orCrohn's disease

    Am J Gastroenterol, Vol: 97 Page: 1415-20 June 2002
    F. Sharif; M. McDermott; M. Dillon; B. Drumm; M. Rowland; C. Imrie; S. Kelleher; S. Harty; B. Bourke

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  • 33.   Foetal brain development in offspring of women with psychosis

    The aim of this study was to whether genetic risk for psychosis related to differences in foetal brain development as measured by prenatal ultrasonography

    Br J Psychiatry, Vol: 190 Page: 445-6 May 2007
    M. C. Clarke; M. Cannon; M. W. Hogg; M. N. Marks; S. Conroy; S. J. Pawlby; A. Greenough; K. Nicolaides

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  • 34.   Genetic polymorphisms of angiotensin system genes in congenital diaphragmatic hernia associated with persistent pulmonary hypertension

    The aim of this study was to investigate the ACE I/D genotype, the M235 T polymorphism of the angiotensinogen gene and the A1166 C polymorphism of AT1R in the lungs of congenital diaphragmatic hernia complicated by persistent pulmonary hypertension

    J Pediatr Surg, Vol: 39 Page: 302-6; discussion 302-6 March 2004
    V. Solari; P. Puri

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  • 35.   HLA class II haplotype and autoantibody associations in children with juvenile dermatomyositis and juvenile dermatomyositis-scleroderma overlap

    The aim of this study was to investigate a large cohort of children with juvenile dermatomyositis, and those with JDM-scleroderma (JDM-SSc) overlap, using detailed serological analysis, HLA class II genotyping and clinical characterization.

    Rheumatology (Oxford), Vol: 46 Page: 1786-91 December 2007
    L. R. Wedderburn; N. J. McHugh; H. Chinoy; R. G. Cooper; F. Salway; W. E. Ollier; L. J. McCann; H. Varsani; J. Dunphy; J. North; J. E. Davidson

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  • 36.   In vivo expression of the 25-kDa laminin-binding protein of Helicobacter pylori

    This aim of this study was to determine whether the 25-kDa protein is produced by Helicobacter pylori in infected hosts

    FEMS Immunol Med Microbiol, Vol: 43 Page: 331-7 March 2005
    A. P. Moran; S. A. Broaders; A. Rapa; G. Oderda

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  • 37.   Increased angiogenesis in bone marrow of children with acute lymphoblastic leukaemia has no prognostic significance

    The aim of this study was to investigate bone marrow trephine biopsies from children with acute lymphoblastic leukaemia at diagnosis and following treatment.

    Br J Haematol, Vol: 118 Page: 991-8 September 2002
    M. A. Pule; C. Gullmann; D. Dennis; C. McMahon; M. Jeffers; O. P. Smith

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  • 38.   Increased expression of mast cells in reflux nephropathy

    The aim of this study was to examine the distribution of mast cells in kidneys with reflux nephropathy and to determine the relationship between mast cells and the interstitial fibrotic process in reflux nephropathy

    Pediatr Nephrol, Vol: 19 Page: 157-63 February 2004
    V. Solari; K. Unemoto; A. Piaseczna Piotrowska; P. Puri

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  • 39.   Influence of a health education intervention on physical activity and screen time in primary school children: 'Switch Off--Get Active'

    This study aimed to evaluate the efficacy of 'Switch Off-Get Active', a 16-week controlled health education intervention, in increasing physical activity and reducing screen time and BMI in primary school children

    J Sci Med Sport, Vol: 9 Page: 388-94 October 2006
    M. Harrison; C. F. Burns; M. McGuinness; J. Heslin; N. M. Murphy

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  • 40.   Leptin concentrations in maternal serum and cord blood in diabetic and nondiabetic pregnancy

    The aim of this study was to examine the relationships between maternal and cord leptin concentrations, maternal and neonatal outcomes, and measures of glycemic control in diabetic and nondiabetic pregnancy

    Am J Obstet Gynecol, Vol: 188 Page: 1326-32 May 2003
    J. G. Manderson; C. C. Patterson; D. R. Hadden; A. I. Traub; H. Leslie; D. R. McCance

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  • 41.   Maternal folate status and neural tube defects in Ireland: the need for a national food fortification program

    This aim of this study was to examine maternal folate status and neural tube defects in Ireland and the need for a national food fortification program

    Ir Med J, Vol: 100 Page: 469-72 May 2007
    T. Walsh; S. O'Broin; S. Cooley; J. Donnelly; C. Collins; H. McMillan; R. F. Harrison; C. McMahon; M. Geary

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  • 42.   MTRR and MTHFR polymorphism: link to Down syndrome?

    The aim of this study was to examine the prevalence of variant genotypes in mothers who had given birth to a child with Down syndrome and in control mothers, and investigated the biochemical factors influenced by the presence of MTRR A66G and MTHFR C677T

    Am J Med Genet, Vol: 107 Page: 151-5 January 2002
    V. B. O'Leary; A. Parle-McDermott; A. M. Molloy; P. N. Kirke; Z. Johnson; M. Conley; J. M. Scott; J. L. Mills

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  • 43.   Neonatal encephalopathy is associated with altered perinatal systemic neutrophil apoptosis

    The aim of this study was to evaluate alterations in perinatal neutrophil phenotype following systemic hypoxia-ischemia compared with normal controls

    Am J Perinatol, Vol: 24 Page: 525-30 October 2007
    E. J. Molloy; A. J. O'Neill; J. J. Grantham-Sloan; M. Sheridan-Pereira; J. M. Fitzpatrick; D. W. Webb; R. W. Watson

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  • 44.   Neurologic and developmental disability at six years of age after extremely preterm birth

    The aim of the study was to compare neurologic and developmental disability at six years of age in infants born extremely preterm

    N Engl J Med, Vol: 352 Page: 9-19 January 2005
    N. Marlow; D. Wolke; M. A. Bracewell; M. Samara

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  • 45.   Ocular toxocariasis in schoolchildren

    The aim of this study was to examine the extent of consultant-diagnosed toxocaral eye disease among a population of schoolchildren

    Clin Infect Dis, Vol: 39 Page: 173-8 July 2004
    B. Good; C. V. Holland; M. R. Taylor; J. Larragy; P. Moriarty; M. O'Regan

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  • 46.   Parent reports of the psychosocial functioning of children with cleft lip and/or palate

    The aim of this study was to determine the opinion of parents regarding the psychosocial functioning of their child with cleft lip and/or palate and to identify predictors of psychosocial functioning

    Cleft Palate Craniofac J, Vol: 44 Page: 304-11 May 2007
    O. Hunt; D. Burden; P. Hepper; M. Stevenson; C. Johnston

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  • 47.   Parental age at delivery, birth order, birth weight and gestational age are associated with the risk of childhood Type 1 diabetes: a UK regional retrospective cohort study

    The aim of this study was to examine perinatal risk factors for childhood Type 1 diabetes

    Diabet Med, Vol: 22 Page: 200-6 February 2005
    C. R. Cardwell; D. J. Carson; C. C. Patterson

    [Preview] [Read]

  • 48.   Parenteral penicillin for children with meningococcal disease before hospital admission: case-control study

    The aim of this study was to explore the impact on mortality and morbidity of parenteral penicillin given to children before admission to hospital with suspected meningococcal disease

    Bmj, Vol: 332 Page: 1295-8 June 2006
    A. Harnden; N. Ninis; M. Thompson; R. Perera; M. Levin; D. Mant; R. Mayon-White

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  • 49.   Polymorphisms within the vitamin B12 dependent methylmalonyl-coA mutase are not risk factors for neural tube defects

    The aim of this study was to examine polymorphisms within the vitamin B12 dependent methylmalonyl-coA mutase are not risk factors for neural tube defects

    Mol Genet Metab, Vol: 80 Page: 463-8 December 2003
    A. Parle-McDermott; E. J. McManus; J. L. Mills; V. B. O'Leary; F. Pangilinan; C. Cox; A. Weiler; A. M. Molloy; M. Conley; D. Watson; J. M. Scott; L. C. Brody; P. N. Kirke

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  • 50.   Potential viral pathogenic mechanism for new variant inflammatory bowel disease

    The aim of this study was to investigate the presence of persistent measles virus in the intestinal tissue of patients with new variant inflammatory bowel disease and controls

    Mol Pathol, Vol: 55 Page: 84-90 April 2002
    V. Uhlmann; C. M. Martin; O. Sheils; L. Pilkington; I. Silva; A. Killalea; S. B. Murch; J. Walker-Smith; M. Thomson; A. J. Wakefield; J. J. O'Leary

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  • 51.   Pregnancy and pregnancy outcome in hepatitis C type 1b

    The aim of this study was to examine health outcomes in women infected with Hep C type 1b during pregnancy with a matched control group

    Qjm, Vol: 93 Page: 597-601 September 2000
    T. Jabeen; B. Cannon; J. Hogan; M. Crowley; C. Devereux; L. Fanning; E. Kenny-Walsh; F. Shanahan; M. J. Whelton

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