Accessibility
Legal Notices
Text Version

Irish Child Health Database - Peer Reviewed Papers

Database Search

How to use this database.

• Method 1- uses a free natural language approach.

  After choosing the object of the search – by ticking title, abstract, aims and objective, or author - enter a term, word or name in the ‘Search’ box to return references answering your research question.

• Method 2 - utilises key words.

  Those key words assigned from thesauruses of controlled vocabulary by the trained coders of international bibliographic databases.
  The controlled vocabularies key word are listed alphanumerically under 'Bibliographic database keywords' .
  Use the drop down menu to identity which 'key words' you are interested in to return references to answer your research question.

• Method 3 - is based on the indexing system

  developed by the researchers who compiled this database.
  It adopts a thematic approach to mapping Irish child health research. The themed areas represent outcomes mapped to the International Classification of Disease version 10 (ICD-10) or one of 23 other health-related themed outcomes. Themes are defined in Tables 5 to 7 (of the study report).
  Use the alphabetic drop down menu under ‘ICD-10 or themed health-related outcomes’ to identity which themed areas you are interested in to select references to answer your research question.

• Method 4 – allows papers to be searched by Study type.

  Indexing by study type offers a valuable insight into understanding the population impact of the topic of interest. More than 20 study types were identified across the 2,152 study papers. These are defined in Table 3 (of the study report). Within 'Study type' papers are further stratification by geographical region (Table 49), topic area of interest and study aims and objectives.
  Click on 'Study type' to select the type of study of interest, progressively select sub-categories by topic area or other sub-classification of interest to answer your research question.

The complete background, methods and findings from this mapping exercise are detailed in the study report.

Abnormalities, Multiple/ pathology

Your search returns 5 documents

• 1.   Cell death in the early adriamycin rat model

  The aim of this study was to investigate the hypothesise of increased cell death in adriamycin-exposed embryos

  

  Abstract:

  The adriamycin rat model (ARM) exhibits many features of the VACTERL association. Adriamycin is a cytotoxic drug used in cancer chemotherapy. Although its exact mode of action is not clear, it is presumed to have a similar cytotoxic role in the developing embryo. Lysotracker red (LT) is a dye that stains phagolysosomes and apoptotic bodies and allows entire rodent embryos to be stained more...

  Categories:

  adriamycin-exposed embryos; increased cell death;

  Geography:

  Republic of Ireland

  Pediatr Surg Int, Vol: 18 Page: 576-80 October 2002
  J. Gillick; S. Giles; J. Bannigan; P. Puri

  [Preview] [Read]

• 2.   Low-grade fibromyxoid sarcoma: yet another malignancy associated with Kabuki syndrome

  This case report discusses Kabuki Syndrome with a confirmed diagnosis of a low grade fibromyxoid sarcoma.

  

  International Classification:

  Syndrome

  Categories:

  Kabuki syndrome

  Geography:

  Republic of Ireland

  Clin Dysmorphol, Vol: 17 Page: 199-202 July 2008
  R. Shahdadpuri; A. O'Meara; M. O'Sullivan; W. Reardon

  [Preview] [Read]

• 3.   Megacystis-microcolon-intestinal hypoperistalsis syndrome: evidence of intestinal myopathy

  The aim of this study was to examine small- and large-bowel specimens of three newborn infants presenting with the clinical and radiological symptoms of megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS)

  

  Abstract:

  We investigated small- and large-bowel specimens of three newborn infants presenting with the clinical and radiological symptoms of megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS). Conventional histological staining revealed marked thinning of the longitudinal muscle layer. Electron-microscopic investigations showed typical "central core" vacuolic more...

  International Classification:

  Syndrome - megacystis-microcolon-intestinal hypoperistalsis

  Categories:

  megacystis-microcolon-intestinal hypoperistalsis syndrome

  Geography:

  Republic of Ireland

  Pediatr Surg Int, Vol: 18 Page: 2-5 January 2002
  U. Rolle; S. O'Briain; R. H. Pearl; P. Puri

  [Preview] [Read]

• 4.   Microgastria-limb reduction anomaly with total amelia

  This case report discusses a 3-year-old girl with severe microgastria and total amelia who has been managed conservatively with minimal surgical intervention.

  

  Abstract:

  The Microgastria-limb reduction anomaly is a rare disorder of unknown aetiology in which microgastria is associated with limb defects, along with splenic and other variable congenital abnormalities. In 15 previously reported cases, none have had the most extreme form of amelia. We report the clinical progress of a 3-year-old girl with severe microgastria and total amelia who has been more...

  International Classification:

  Other - microgastria

  Categories:

  microgastria

  Geography:

  Northern Ireland

  Clin Dysmorphol, Vol: 11 Page: 187-90 July 2002
  C. Stewart; M. Stewart; F. Stewart

  [Preview] [Read]

• 5.   Septo-optic dysplasia with digital anomalies--a recurrent pattern syndrome

  This case report discusses a 3 year old boy with Septo-optic dysplasia and digital anomalies

  

  Abstract:

  A distinct form of septo-optic dysplasia (SOD) comprises limb malformations in addition to the characteristic CNS and ocular abnormalities. To date, there have been 4 reports, citing 5 affected patients with this combined phenotype. We now add a further case and present neuroradiological images of the CNS findings in this condition. The striking consistency of the limb malformations and more...

  International Classification:

  Diseases of the eye and adnexa - Report

  Categories:

  Septo-optic dysplasia

  Geography:

  Republic of Ireland

  Am J Med Genet A, Vol: 131 Page: 82-5 November 2004
  I. M. Harrison; D. Brosnahan; E. Phelan; R. J. Fitzgerald; W. Reardon

  [Preview] [Read]