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Irish Child Health Database - Peer Reviewed Papers

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Irish Child Health Database » » D » Dermatitis, Atopic/ genetics/metabolism

Dermatitis, Atopic/ genetics/metabolism

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1. Breaking the (un)sound barrier: filaggrin is a major gene for atopic dermatitis

This article discusses a gene for atopic dermatitis

Abstract:

We have recently shown that loss-of-function mutations in the filaggrin gene, carried by about 10% of people of European ethnicity, cause ichthyosis vulgaris and are strong predisposing factors for atopic dermatitis and asthma secondary to atopic dermatitis. These results demonstrate a prominent role for the epidermal barrier in atopic disease and have important implications for the more...

Geography:

Republic of Ireland

J Invest Dermatol, Vol: 126 Page: 1200-2 June 2006
A. D. Irvine; W. H. McLean

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