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Irish Child Health Database - Peer Reviewed Papers

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Irish Child Health Database » » A » Antibiotics, Antineoplastic/toxicity

Antibiotics, Antineoplastic/toxicity

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1. The Adriamycin rat/mouse model and its importance to the paediatric surgeon

This article discusses adriamycin rat/mouse model and its importance to the paediatric surgeon

Abstract:

The teratogenic effect of Adriamycin (doxorubicin) in the rat model, and more recently in the mouse, has provided paediatric surgeons with a reliable, easily reproducible method of studying the embryology and molecular biology for a range of complex congenital anomalies. Concomitantly these animal models have stimulated interest among embryologists for the effect on the notochord, more...

Geography:

Republic of Ireland

Pediatr Surg Int, Vol: 24 Page: 113-8 January 2008
J. Gillick; A. Mortell; M. Dawrant; S. Giles; J. Bannigan; P. Puri

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