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Irish Child Health Database - Peer Reviewed Papers

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Irish Child Health Database » » N » Nitric Oxide Synthase/ genetics/metabolism

Nitric Oxide Synthase/ genetics/metabolism

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1. Expression of vasoactive mediators during mechanical ventilation in nitrofen-induced diaphragmatic hernia in rats

The aim of this study was to investigate mRNA expression of ET-1, eNOS, and CGRP in congenital diaphragmatic hernia lung in the perinatal period

Abstract:

The high mortality in patients with congenital diaphragmatic hernia (CDH) has been attributed to pulmonary hypoplasia and persistent pulmonary hypertension (PPH). Endothelin-1 (ET-1), nitric oxide (NO), and calcitonin gene-related peptide (CGRP) have been reported to be important vasoactive mediators in the perinatal pulmonary circulation. The exact mechanism by which these vasoactive more...

Categories:

mRNA expression; congenital diaphragmatic hernia lung

Geography:

Republic of Ireland

Pediatr Surg Int, Vol: 21 Page: 143-7 March 2005
T. Shinkai; H. Shima; V. Solari; P. Puri

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