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This study examined recombinant factor VIIa in the management of surgery and acute bleeding episodes in children with haemophilia and high-responding inhibitors
Abstract:
The development of inhibitors to therapeutic factor concentrates in children with haemophilia A or B is a troublesome complication of factor replacement therapy. Immune tolerance protocols have been developed to eliminate the inhibitors, and these are successful in approximately 80% of children. However, acute bleeding episodes require treatment with a factor (F)VIII or FIX bypassing more...
International Classification:
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism - Coagulation defects, purpura and other haemorrhagic conditions - haemophilia
Categories:
haemophilia
Geography:
Republic of Ireland
Pathophysiol Haemost Thromb,
Vol: 32 Suppl 1 Page: 22-5 2002
O. P. Smith
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