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Irish Child Health Database - Peer Reviewed Papers

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Irish Child Health Database » » A » Antimetabolites/administration & dosage

Antimetabolites/administration & dosage

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1. Antenatal dexamethasone administration inhibits smooth-muscle-cell DNA synthesis in pulmonary-arterial media in nitrofen-induced congenital diaphragmatic hernia in rats

The aim of this study was to investigate the effect of antenatal glucocorticoid therapy on smooth-muscle-cell DNA synthesis in the pulmonary arteries in a nitrofen-induced congenital diaphragmatic hernia rat model following nitrofen admin

Abstract:

The aim of this study was to investigate the effect of antenatal glucocorticoid therapy on smooth-muscle-cell (SMC) DNA synthesis in the pulmonary arteries (PA) in a nitrofen-induced congenital diaphragmatic hernia (CDH) rat model following nitrofen administration on day 9.5 of gestation. Antenatal dexamethasone (DEX) was given intraperitoneally on days 18.5 and 19.5 of gestation. more...

Categories:

antenatal glucocorticoid therapy; congenital diaphragmatic hernia

Geography:

Republic of Ireland

Pediatr Surg Int, Vol: 16 Page: 414-6 2000
Y. Taira; H. Shima; E. Miyazaki; K. Ohshiro; P. Puri

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