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Irish Child Health Database - Peer Reviewed Papers

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You are here: Irish Child Health Database » Study Papers » Descriptive Studies - With a comparative dimension: time, geography, treatment, procedures » Comparison Study
  • Pregnancy and perinatal outcomes after assisted reproduction: a comparative study

    Published in:

    Ir J Med Sci, Vol: 177, Page: 233-41

    Publication Date:

    September 2008

    Aims & Objectives:

    The aim of this study was to quantify the risk of adverse perinatal outcomes birth defects and pregnancy complications following assisted reproductive technology

    Abstract:

    BACKGROUND: Increasing use of fertility therapy has elicited concerns regarding adverse effects for expectant mothers and the health of children thus conceived. AIMS: To study the risk of adverse perinatal outcomes, birth defects and pregnancy complications following assisted reproductive technology (ART). METHODS: Questionnaire-based study involving 1,524 children and 1,182 pregnancies conceived following in vitro fertilisation (IVF) in two units. Outcomes were compared with the general population. RESULTS: In the study group versus the general population; multi-foetal gestations, 26 versus 2%; singleton preterm delivery and low birth weight, 8.7 and 6.4 versus 4.3 and 4%, respectively; non-lethal congenital malformation rate, 2.6 versus 2.1%; placenta praevia, 2.8 versus 0.5%. CONCLUSIONS: Multi-foetal gestations remain the principal cause of adverse perinatal outcomes after ART. Singleton ART pregnancies have an increased risk of preterm delivery and low birth weight at term. Non-lethal congenital malformation rates are not increased following ART. Placenta praevia is increased following ART.

    Authors:

    C. Allen; S. Bowdin; R. F. Harrison; A. G. Sutcliffe; L. Brueton; G. Kirby; J. Kirkman-Brown; C. Barrett; W. Reardon; E. Maher

    Study Type:

    Study Papers » Comparison Study » Descriptive Studies - With a comparative dimension: time, geography, treatment, procedures

    Categories:

    assisted reproductive technology

    International Classification:

    Pregnancy, childbirth and the puerperium

    Keywords:


    Geography:

    International (Dublin/Birmingham)