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Irish Child Health Database - Peer Reviewed Papers

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You are here: Irish Child Health Database » Study Papers » Descriptive Studies - With a comparative dimension: time, geography, treatment, procedures » Epidemiology - descriptive, incidence, prevalence and/or trends
  • Toward the effective surveillance of hypospadias

    Published in:

    Environ Health Perspect, Vol: 112, Page: 398-402

    Publication Date:

    March 2004

    Aims & Objectives:

    The aim of this study was to describe the prevalence of hypospadias from 1980 to 1999 in 20 regions of Europe with EUROCAT (European Surveillance of Congenital Anomalies)

    Abstract:

    Concern about apparent increases in the prevalence of hypospadias--a congenital male reproductive-tract abnormality--in the 1960s to 1980s and the possible connection to increasing exposures to endocrine-disrupting chemicals have underlined the importance of effective surveillance of hypospadias prevalence in the population. We report here the prevalence of hypospadias from 1980 to 1999 in 20 regions of Europe with EUROCAT (European Surveillance of Congenital Anomalies) population-based congenital anomaly registers, 14 of which implemented a guideline to exclude glanular hypospadias. We also report data from the England and Wales National Congenital Anomaly System (NCAS). Our results do not suggest a continuation of rising trends of hypospadias prevalence in Europe. However, a survey of the registers and a special validation study conducted for the years 1994-1996 in nine EUROCAT registers as well as NCAS identified a clear need for a change in the guidelines for registration of hypospadias. We recommend that all hypospadias be included in surveillance, but that information from surgeons be obtained to verify location of the meatus, and whether surgery was performed, in order to interpret trends. Investing resources in repeated special surveys may be more cost-effective than continuous population surveillance. We conclude that it is doubtful whether we have had the systems in place worldwide for the effective surveillance of hypospadias in relation to exposure to potential endocrine-disrupting chemicals.

    Authors:

    H. Dolk; M. Vrijheid; J. E. Scott; M. C. Addor; B. Botting; C. de Vigan; H. de Walle; E. Garne; M. Loane; A. Pierini; S. Garcia-Minaur; N. Physick; R. Tenconi; A. Wiesel; E. Calzolari; D. Stone

    Study Type:

    Study Papers » Epidemiology - descriptive, incidence, prevalence and/or trends » Descriptive Studies - With a comparative dimension: time, geography, treatment, procedures

    Categories:

    hypospadias

    International Classification:

    Congenital malformations, deformations and chromosomal abnormalities - hypospadias

    Keywords:


    Geography:

    International ( 20 regions of Europe with EUROCAT)