Accessibility
Legal Notices
Text Version

Irish Child Health Database - Peer Reviewed Papers

Database Search

How to use this database.

• Method 1- uses a free natural language approach.

  After choosing the object of the search – by ticking title, abstract, aims and objective, or author - enter a term, word or name in the ‘Search’ box to return references answering your research question.

• Method 2 - utilises key words.

  Those key words assigned from thesauruses of controlled vocabulary by the trained coders of international bibliographic databases.
  The controlled vocabularies key word are listed alphanumerically under 'Bibliographic database keywords' .
  Use the drop down menu to identity which 'key words' you are interested in to return references to answer your research question.

• Method 3 - is based on the indexing system

  developed by the researchers who compiled this database.
  It adopts a thematic approach to mapping Irish child health research. The themed areas represent outcomes mapped to the International Classification of Disease version 10 (ICD-10) or one of 23 other health-related themed outcomes. Themes are defined in Tables 5 to 7 (of the study report).
  Use the alphabetic drop down menu under ‘ICD-10 or themed health-related outcomes’ to identity which themed areas you are interested in to select references to answer your research question.

• Method 4 – allows papers to be searched by Study type.

  Indexing by study type offers a valuable insight into understanding the population impact of the topic of interest. More than 20 study types were identified across the 2,152 study papers. These are defined in Table 3 (of the study report). Within 'Study type' papers are further stratification by geographical region (Table 49), topic area of interest and study aims and objectives.
  Click on 'Study type' to select the type of study of interest, progressively select sub-categories by topic area or other sub-classification of interest to answer your research question.

The complete background, methods and findings from this mapping exercise are detailed in the study report.

• Cardiomyopathy and cardiomegaly in stillborn infants of diabetic mothers

  Published in:

  Pediatr Dev Pathol, Vol: 11, Page: 10-4

  Publication Date:

  2008 Jan-Feb

  Aims & Objectives:

  The aim of the study was to examine the cardiomyopathy and cardiomegaly in stillborn infants of diabetic mothers

  Abstract:

  To report the incidence of cardiomegaly in stillborn normally formed infants of mothers with diabetes mellitus. This is a retrospective study with institutional ethics approval. The presence of cardiomegaly was recorded in stillborn infants of diabetic mothers (N = 27) and compared with that recorded in stillborn large-for-gestational age (LGA > 90th percentile, n = 18) and stillborn appropriately grown (10th to 90th percentiles, n = 107) nondiabetic infants. Blinded to the clinical details, the histology slides were reviewed to measure cardiac wall thickness and to record the presence or absence of myocardial fiber disarray. Stillborn infants of mothers with diabetes mellitus, when compared with appropriately grown stillborn nondiabetic infants and when adjusted for birth weight, had heavier hearts, thicker ventricular free wall measurements, and lighter brains. While cardiomegaly was reported in 22% of stillborn LGA infants, comparison with stillborn appropriately grown infants revealed no difference in heart weights corrected for birth weight. Comparison of LGA nondiabetic infants with stillborn diabetes mellitus infants revealed greater actual heart weight/expected for birth weight (P < 0.05) and lighter brains (actual brain weight/expected for birth weight, P < 0.05) in the diabetes mellitus group. Cardiomegaly is a common finding in stillborn infants of mothers with diabetes mellitus and may contribute to the risk of fetal death in these pregnancies.

  Authors:

  N. E. Russell; P. Holloway; S. Quinn; M. Foley; P. Kelehan; F. M. McAuliffe

  Study Type:

  Study Papers » Comparison Study » Descriptive Studies - With a comparative dimension: time, geography, treatment, procedures

  International Classification:

  Pregnancy, childbirth and the puerperium

  Keywords:

  • Brain/pathology
  • Cardiomegaly/ epidemiology/pathology
  • Cardiomyopathies/ epidemiology/pathology
  • Diabetes, Gestational/epidemiology
  • Female
  • Fetal Death/epidemiology
  • Fetal Diseases/pathology
  • Gestational Age
  • Heart Septal Defects/pathology
  • Humans
  • Incidence
  • Infant, Newborn
  • Ireland/epidemiology
  • Pregnancy
  • Pregnancy in Diabetics
  • Retrospective Studies
  • Risk Factors
  • Stillbirth/ epidemiology

  
  

  Geography:

  Republic of Ireland (National Maternity Hospital Dublin)