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Irish Child Health Database - Peer Reviewed Papers

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You are here: Irish Child Health Database » Study Papers » Descriptive Studies - Studies with a health technology dimension » Screening Study
  • Cholesterol screening in an at-risk pediatric population

    Published in:

    Pediatr Cardiol, Vol: 29, Page: 609-13

    Publication Date:

    May 2008

    Aims & Objectives:

    The aim of this study was to evaluate the frequency of elevated low-density lipoprotein cholesterol in children and adolescents (8-18 years) in whom one parent had a history of premature ischemic heart disease (<55 years)

    Abstract:

    Elevation of low-density lipoprotein (LDL) cholesterol is a recognized risk factor for premature atherosclerosis and such elevations have their antecedents in the pediatric population. This study evaluated the frequency of elevated LDL cholesterol in children and adolescents (8-18 years) in whom one parent had a history of premature ischemic heart disease (<55 years). Patients had a fasting lipid profile performed and results were classified as normal, borderline/high, or high in accordance with the American Academy of Pediatrics (AAP) guidelines. Fifty-two parents had a total of 97 children and adolescents who were eligible for screening. Ninety-three initially consented and fasting lipid profiles were obtained in 82 (84.5%) children. Prevalences of high and borderline/high LDL cholesterol were (7/82) 8.5% and (17/82) 20.7%, respectively. Screening for hypercholesterolemia in these at-risk children and adolescents is prudent and dietary advice must be offered.

    Authors:

    M. J. O'Grady; A. M. Brown; M. B. O'Neill

    Study Type:

    Study Papers » Screening Study » Descriptive Studies - Studies with a health technology dimension

    Categories:

    low-density lipoprotein cholesterol; premature ischemic heart disease

    International Classification:

    Diseases of the circulatory system - Ischemic heart disease

    Keywords:


    Geography:

    Republic of Ireland (Mayo)